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Zyban. Zyban is a sustainedrelease medication that is nicotinefree and is used to help one stop smoking Before taking Zyban tell your doctor of all nonprescription and prescription medications you may use especially MAO inhibitors (eg, isocarboxazid, phenelzine UCSF School of Pharmacy. medicine question of the month: Zyban. August 2002.

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