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Buproprion, Wellbutrin, Zyban. Don St. John, PA Adult Outpatient Psychiatry University of Iowa Department of Psychiatry Doctors monitoring the safety of Zyban, an antismoking drug, have reported the deaths of 18 patients who had been prescribed the medicine side effects of zyban, 6, curious721, 379, Aug 26, 2003 3:52pm Pigz View latest post. Zyban helped me quit after 10 years of smoking Not sure about Zyban?